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research day 2026: our master student made an impression

30/3/2026

 
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Biomedical Master students Arnaud Thomaes and Elena De Rijbel presented their research today, showcasing scientific maturity, curiosity, and dedication. It’s inspiring to see young scientists communicate their work so clearly and confidently. Well done to both, and mentor Charlotte Matton & supervisor Miriam Bauwens and to everyone contributing to this research community! All this resulted in a happy PI. 

ATTending the Vsd meeting in crete

27/3/2026

 
PhD students Charlotte and Hannes recently made their way to Crete, Greece, for the International Symposium on Vertebrate Sex Determination (VSD). While the weather didn’t quite match the postcard-perfect expectations, the meeting more than made up for it with great science, familiar faces, and plenty of new connections!

Hannes shared his latest findings in a poster, where he identified novel SOX9 regulatory deletions overlapping with enhancer regions.
Charlotte presented her work on mapping the gene regulatory landscape in human adult granulosa cells, and took home the award for Best Oral Presentation 🎉.

All in all, a very successful  meeting, with lots of inspiration and ideas to bring back home!

Honorary doctorate jean bennett

22/3/2026

 
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Proud to announce that professor Jean Bennett will receive an honorary doctorate from UGent Ghent University and is promoted by the Faculty of Medicine and Health Sciences of Ghent University. Professor Bennett is a world-renowned leader in gene therapy for inherited blindness. Her groundbreaking work, restoring sight to patients with retinal diseases, has transformed medicine.

Our lab also had the privilege of co-promoting prof. Bennett for her honorary doctorate and has cohosted a meet&greet as well as a minisymposium to accompany this occasion. 

Teamwork in the snow

8/1/2026

 
Thanks to heavy snowfall and cold temperatures, our team and collaborators from neighboring labs were able to work on an unorthodox project together. Thanks to a team effort a new lab, but very temporary, lab mascotte was built.

Funds for research in ophthalmology honors Eline

8/12/2025

 
Elfride represented laureate Eline Geens at the Funds for Research in Ophthalmology awarding ceremony. Eline and her project 'Charaterization and CRISPR-correction of a novel dominant Belgian RPE65-maculopathy using patient-derived iPSC-RPE models' were the awarded the FRO prize this year. Congrats Eline! 
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Congrats dr. De Bruycker

24/10/2025

 
We welcome a new doctor as Edith has defended her PhD thesis titled: 'Multi-level exploration of the photoreceptor-specific nuclear receptor NR2E3 implicated in autosomal dominant retinitis pigmentosa'. It gets better: Edith will start as a postdoc with one of her copromotors, Frauke Coppieters who runs the TaRGeT group.

A digital copy can be found here. 

ESHG Webinar - Multi-omics in inherited eye diseases: from missing heritability to new therapeutic opportunities

14/10/2025

 
Elfride is providing insigthts in multi-omics and hereditary eye disease as part of a webinar series organized by the European Society of Human Genetics. Don't miss this and join Elfride on October 29! More info can be found here. 
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doctor golden retriever, well done!

9/10/2025

 
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Alex Segers, our golden retriever according to his lab totem, has succesfully defended his thesis 'Dimensionality Reduction and Outlier Detection for Transcriptomics and Proteomics Data'. We are sad to see Alex leave, but wish him all the best at J&J. 

The thesis is made available here.

International Symposium on Retinal Degeneration

30/9/2025

 
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PhD students Eline Van Vooren and Eline Geens attended the Retinal Degeneration (RD) meeting in Prague, an exciting international conference bringing together scientists and clinicians dedicated to understanding and treating retinal diseases.

Eline Van Vooren showcased her work on the identification & functional characterization of a novel dominant
RPE65 variant.

Meanwhile, Eline Geens presented her research on the pathomechanism of this dominant
RPE65 variant using patient-derived iPSC-RPE cells.

Their presentations sparked engaging discussions and highlighted the group’s contributions to advancing knowledge in inherited retinal disorders. 

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progret meeting nijmegem

21/9/2025

 
As part of the ProgRET training program (https://www.progret.eu/), PhD student Nelson Martins, traveled to RadboudUMC in Nijmegen, Netherlands. Nelson participated in both research-focused and complementary skills training sessions, covering topics such as bioinformatics, functional genomics, multi-omics, project management, and  career development.

The ProgRET Network Meetin , also held in Nijmegen, brought together all doctoral candidates and their supervisors, prof. Elfride De Baere and postdoc Miriam Bauwens in Nelson's case, to review and discuss the progress of ongoing projects.

Additionally, Prof. Elfride De Baere and dr. Miriam Bauwens attended the Farewell Symposium for prof. Frans Cremers, a long-standing and highly valued collaborator of our lab, whose remarkable career spans more than 40 years.

GoOD meeting 2025 in Ghent

10/9/2025

 
Building on the success of the last five Genetics of Ocular Development (GoOD) Meetings, the 2025 meeting was held in the beautiful city of Ghent, organized by lab De Baere. All participants had two stimulating days of science combined with an enjoyable social program. 

More info and pictures can be found on here.

ENHANCE-MCOR funded by the GENeHOPE Fund

2/9/2025

 
The ENHANCE-MCOR project, led by Prof. Elfride De Baere (Ghent University) and Dr. Jean-Michel Rozet (Institut Imagine), was funded by the GENeHOPE Fund. This research tackles microcoria (MCOR), a rare genetic disorder marked by abnormally small pupils, light sensitivity, and often progression to severe glaucoma. The cause? Disruptions in the “dark matter” of our DNA, the non-coding regions that regulate gene activity. Since current mouse models cannot reproduce MCOR, researchers are turning to an unexpected ally: the frog Xenopus tropicalis. Its eye develops much like ours, making it a powerful model to uncover how these DNA disruptions trigger MCOR and glaucoma. By doing so, the project could not only shed light on this rare blinding disease, but also pave the way for new treatments benefiting children and adults with glaucoma worldwide.
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EMBO Enhanceropathies 2025, we were there!

22/6/2025

 
Our lab participated in the EMBO Workshop on Enhancer Mechanics and Enhanceropathies (https://meetings.embo.org/event/25-enhanceropathies), held at the historic Hindsgavl Castle in Middelfart, Denmark. This international workshop focused on the fundamental mechanisms of transcriptional enhancers and chromatin structure, and explored how enhancer dysfunction contributes to human diseases. PhD student Nelson and post-doctoral fellow Eva D’haene presented their research during the poster sessions. Prof. Elfride De Baere delivered a talk titled “Decoding the Role of Ultraconserved and Functionally Conserved Regulatory Elements in Rare Eye Enhanceropathies”, highlighting the lab’s work on understanding the regulatory mechanisms underlying rare genetic eye disorders.

This event provided a valuable platform to exchange ideas with leading experts and strengthen collaborations in the field of enhancer biology. 

our team at the ESHG meeting in milan

25/5/2025

 
In May 2025, our team participated in the European Society of Human Genetics (ESHG) Meeting in Milan. PhD students Eline and Charlotte had the opportunity to present their research, while Prof. Elfride De Baere delivered an inspiring keynote lecture on multi-omics approaches in inherited retinal diseases.

ARVO 2025, we were present!

11/5/2025

 
During the Association for Research in Vision and Ophthalmology’s annual meeting in Salt Lake City, Utah, post-doctoral fellow Miriam Bauwens shared new findings on a previously unrecognized isoform of ABCA4, the gene that causes Stargardt disease. Needless to say, we had a happy PI. 
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De Baere Lab © 2025
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